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Stem Cells and Wrinkle Control

Back in 2009 the likes of Helen Mirren and Jennifer Lopez were early celebrity adopters of the benefits of using the stem cells of swiss green apples. At the time, studies were emerging into the mainstream media that indicated the benefits of stem cells in skin care and companies were starting to put forward products that included them. Plant stem cells emerged as the cutting edge of dermatological science, and key among those plants were these rare fruits.

The Science of Green Apple Stem Cells

A 2009 study indicated that using stem cells for 4 weeks could reduce the appearance of fine lines and wrinkles. (Source). This study, along with the production of very expensive cosmetic skincare lines and the celebrity endorsements, caught the attention of some pretty major world media.

“Could the extract from a rare Swiss apple REALLY get rid of your wrinkles?” asked, a UK based news outlet. Their answer was yes. The explanation was that because human stem cells are banned from use in cosmetics, scientists turned to plants to see if they could accomplish results that would have them “interact with human skin stem cells, eliminate wrinkles, and make skin look younger.”

These plant stem cells work as follows:

  • The actions of both human and plant stem cells are dictated by the environment, not by the cells’ internal programming. For instance, isolated plant stem cells are able to form entire plant organs when exposed to the right signaling factors.

  • Plant stem cells are able to detect genetic damage in their environment, and kill off those damaged cells before the damage spreads.

  • Small but significant changes have been detected in human skin after using plant stem cells. After two weeks of using a product containing these plant stem cell extracts, consumers have seen a significant reduction in the depth of crow’s feet wrinkles by 8 percent; the reduction in the depth of crow’s feet after four weeks reached 15 percent. Unfortunately, this study did not compare the effects to those with a placebo cream.

The Reason Plants Are Anti-Aging


The idea behind the early technology that incorporated swiss green apple stem cells was that they assure “longevity and combats chronological aging while delaying senescence of skin cells, preserving the youthful look and vitality of one’s skin.” (Source). The science has advanced in the last decade and is resulting in more effective products. In fact, the National Institutes of Healthpublished a study in which the authors note that, “It could be considered that: ‘an apple a day can keep aging skin away and perhaps help regenerate skin.” That article describes the skin aging process and how plant stem cells counteract it.

Plants are equipped with a robust mechanism for regeneration of their tissues under stress. Significant efforts have been put into understanding this mechanism in the expanding field of plant biotechnology. In animals, tissue regeneration occurs following a wound stimulus, resulting in the initiation of organ repair. By contrast, the regenerative efforts made by the plants are not only for tissue repair from damage, but also for the development of a new plant. In other words, cutting the branch of a tree also results in a new bud/branch growth.

Aging of skin is a complex process involving all layers of the epidermis and dermis, comprising denaturing proteins and reduced functioning of regenerative stem cells. Stem cell location in the epidermis is divided into basal layer stem cells and interfollicular stem cells. A decline in the function of epidermal stem cells has been observed in association with shortened telomeres, which reduced proliferative potential in response to UV exposure leading to premature skin aging and senescence. Telomeres are nucleoprotein complexes that cap and save the ends of chromosomes from degradation and abnormal recombination. Telomeres shorten with each cell division and progressive telomere shortening ultimately results in cellular senescence. The question therefore is “Can plant phytohormones have the antioxidant and regenerative ability to prevent this aging process in human skin?”

The Best Green Apple Stem Cell Technology

Mibelle Biochemistry has developed a novel technology enabling the cultivation of this rare species. Thanks to the technology called PhytoCellTecTM, plant stem cells can be obtained and incorporated into cosmetic products to ensure the longevity of skin cells.


Specifically, as noted on our website, these stem cells work to:

  • Diminish the appearance of lines and wrinkles

  • Remove dead skin cells

  • Tighten pores

  • Fade age spots and acne marks

  • Remove blemishes

  • Balance skin tone

  • Rehydrate skin with proteins and nutrients to alleviate sagging, dry skin

Empower yourself to be as Simply Beautiful as you can be and take advantage of this technology today with Sabrina Collagen Rx Plus Anti Aging Face Cream.



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